ERCC3 antibody

Catalog No. ABIN5697525

This anti-ERCC3 antibody is a Rabbit Polyclonal antibody detecting ERCC3 in WB, ELISA and IP. Suitable for Human, Rat and Mouse.

Quick Overview for ERCC3 antibody (ABIN5697525)

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-ERCC3 Antibody

Purpose: ERCC3 antibody

Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ERCC3

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Alternative Name: ERCC3

Background:

Synonyms: General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB)|Basic transcription factor 2 89 kDa subunit (BTF2 p89)|DNA excision repair protein ERCC-3|DNA repair protein complementing XP-B cells|TFIIH basal transcription factor complex 89 kDa subunit (TFIIH 89 kDa subunit, TFIIH p89)|Xeroderma pigmentosum group B-complementing protein|ERCC3|XPB|XPBC

Background: This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Molecular Weight: 89 kDa

Gene ID: 2071

UniProt: P19447

Pathways: DNA Damage Repair